Recent Publications

Pro-fibrotic compounds induce stellate cell activation, ECM-remodelling and Nrf2 activation in a human 3D-multicellular model of liver fibrosis

Prestigiacomo V
Weston A
Messner S
Lampart F
Suter-Dick L
PLoS One
30/06/2017

Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis

Frontiers in Pharmacology
14/06/2017

Intoxication by gamma hydroxybutyrate and related analogues: Clinical characteristics and comparison between pure intoxication and that combined with other substances of abuse [Epub ahead of print]

Miró Ò
Galicia M
Dargan P
Dines AM
Giraudon I
Heyerdahl F
Hovda KE
Yates C
Wood DM
Euro-DEN Research Group
Toxicology Letters
01/06/2017

Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072 [Epub ahead of print]

Paech F
Messner S
Spickermann J
Wind M
Schmitt-Hoffmann AH
Witschi AT
Howell BA
Church RJ
Woodhead J
Engelhardt M
Maurer M
Archives of Toxicology
23/05/2017

The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG [Epub ahead of print]

Grünig D
Felser A
Toxicology in Vitro
16/05/2017

Hepatocellular Toxicity of Imidazole and Triazole Antimycotic Agents

Haegler P
Joerin L
Toxicological Sciences
01/05/2017

Potential mechanisms of development-dependent adverse effects of the herbicide paraquat in 3D rat brain cell cultures [Epub ahead of print]

Zoia D
Schilt C
Greggio C
Fournier M
Do KQ
Neurotoxicology
30/04/2017

OECD/EFSA Workshop on Developmental Neurotoxicity (DNT): The Use of Non-Animal Test Methods for Regulatory Purposes

Fritsche E
Crofton KM
Hernandez AF
Hougaard Bennekou S
Bal-Price A
Reaves E
Terron A
Solecki R
Gourmelon A
ALTEX
31/03/2017

Development and characterization of a human embryonic stem cell-derived 3D neural tissue model for neurotoxicity testing [Epub ahead of print]

Eggermann E
Charvet I
Toni N
Greggio C
Toxicology In Vitro
28/02/2017

Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice

Haegler P
Grünig D
Berger B
PLoS One
30/01/2017