29 Mar 2021
New OECD Guidance document on the "Characterisation, validation and reporting of Physiologically Based Kinetic (PBK) models for regulatory purposes"
OECD Series on Testing and Assessment No. 331; Environment, Health and Safety, Environment Directorate.
This guidance document provides insights into how the data generated by in vitro and in silico (non-animal) methods can be applied to construct physiologically based kinetic (PBK) models and how these models can be validated.