22 Jul 2020

Retinoid AOP funding - call for tender by the Belgian REACH Competent authority, deadline 11 September 2020

The Belgian REACH Competent authority launched a call for tender to develop ADVERSE OUTCOME PATHWAYS (AOPs) on inhibition of retinol/alcohol dehydrogenase (RDH/ADH) during foetal development leading to urogenital or cardiovascular malformations.

Belgium is working on chemical substances which are suspected to disrupt the retinoic acid pathway. Based on the identification of possible biological plausible link(s) between the molecular initiating event and the adverse effect(s), the objective of the work will be to provide a better understanding of the retinoic acid pathway disruption. The AOP, AOPs or AOP network that will be developed are intended to support future regulatory actions in this domain.

Offers have to be submitted by 11 September 2020.

See further information.