Publications

Activation of retinoic acid-related orphan receptor γ(t) by parabens and benzophenone UV-filters [online ahead of print]

Inderbinen SG, Kley M, Zogg M, Sellner M, Fischer A, Kędzierski J, Boudon S, Jetten AM, Smieško M, Odermatt A

Toxicology,  23 Mar 2022


Adverse Outcome Pathways in reproductive and developmental toxicology

Tanabe S, Sachana M, FitzGerald R.

Pp. 63-74 in Gupta RC (Ed.), Reproductive and Developmental Toxicology, 3rd edition. Academic Press 2022,  18 Fév 2022


An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat [online ahead of print]

Nunes C, Singh P, Mazidi Z, Murphy C, Bourguignon A, Wellens S, Chandrasekaran V, Ghosh S, Zana M, Pamies D, Thomas A, Verfaillie C, Culot M, Dinnyes A, Hardy B, Wilmes A, Jennings P, Grillari R, Grillari J, Zurich MG, Exner T.

Toxicology in Vitro,  16 Fév 2022


Scientific Opinion of the Scientific Panel on Plant Protection Products and their Residues (PPR Panel) on testing and interpretation of comparative in vitro metabolism studies

EFSA Panel on Plant Protection Products and their Residues (EFSA PPR Panel); Hernandez-Jerez AF, Adriaanse P, Aldrich A, Berny P, Coja T, Duquesne S, Focks A, Marinovich M, Millet M, Pelkonen O, Pieper S, Tiktak A, Topping CJ, Widenfalk A, Wilks M, Wolterink G, Gundert-Remy U, Louisse J, Rudaz S, Testai E, Lostia A, Dorne JL, Parra Morte JM

EFSA Journal,  23 Déc 2021


Guidance document on Good Cell and Tissue Culture Practice 2.0 (GCCP 2.0) [online ahead of print]

Pamies D, Leist M , Coecke S, Bowe G, Allen DG, Gstraunthaler G, Bal-Price A, Pistollato F, de Vries RBM, Hogberg HT, Hartung T, Stacey G

ALTEX,  9 Déc 2021


Development of the SciRAP Approach for Evaluating the Reliability and Relevance of in vitro Toxicity Data

Roth N, Zilliacus J, Beronius A

Frontiers in Toxicology - Regulatory Toxicology,  15 Oct 2021


The antidepressant Sertraline inhibits CatSper Ca2+ channels in human sperm

Rahban R, Rehfeld A, Schiffer C, Brenker C, Egeberg Palme DL, Wang T, Lorenz J, Almstrup K, Skakkebaek NE, Strünker T, Nef S

Human Reproduction,  18 Sep 2021


Identification of miR-199a-5p, miR-214-3p and miR-99b-5p as Fibrosis-Specific Extracellular Biomarkers and Promoters of HSC Activation

Messner CJ, Schmidt S, Özkul D, Gaiser C, Terracciano L, Krähenbühl S, Suter-Dick L

International Journal of Molecular Sciences,  10 Sep 2021


Human IPSC-Derived Model to Study Myelin Disruption

Chesnut M, Paschoud H, Repond C, Smirnova L, Hartung T, Zurich MG, Hogberg HT, Pamies D

International Journal of Molecular Sciences,  31 Aoû 2021


Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology [online ahead of print]

Harrill JA, Viant MR, Yauk CL, Sachana M, Gant TW, Auerbach Scott S, Beger RD, Bouhifd M, O'Brien J, Burgoon L, Caiment F, Carpi D, Chen T, Chorley BN, Colbourne J, Corvi R, Debrauwer L, O'Donovan C, Ebbels TMD, Ekman DR, Faulhammer F, Gribaldo L, Hilton GM, Jones SP, Kende A, Lawson TN, Leite SB, Leonards PEG, Luijten M, Martin A, Moussa L, Rudaz S, Schmitz O, Sobanski T, Strauss V, Vaccari M, Vijay V, Weber RJM, Williams AJ, Williams A, Thomas RS, Whelan M

Regulatory Toxicology and Pharmacology,  29 Jul 2021