Publications
Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells
Grünig D, Duthaler U, Krähenbühl S
Frontiers in Pharmacology, 23 Avr 2018
Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines
Mingard C, Paech F, Bouitbir J, Krähenbühl S
Journal of Applied Toxicology, 31 Mar 2018
Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis
Engeli RT, Fürstenberger C, Kratschmar DV, Odermatt A
Heliyon, 28 Fév 2018
Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells
Paech F, Mingard C, Grünig D, Abegg VF, Bouitbir J, Krähenbühl S
Toxicology, 15 Fév 2018
Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software
Marsousi N, Desmeules JA, Rudaz S, Daali Y
Biopharmaceutics & Drug Disposition, 31 Jan 2018
An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition
Terron A, Bal-Price A, Paini A, Monnet-Tschudi F, Bennekou SH, EFSA WG EPI1 Members, Leist M, Schildknecht S
Archives of Toxicology, 31 Jan 2018
Navigating in vitro bioactivity data: investigating available resources using model compounds
Ilmjarv S, Augsburger F, Tjalling Bolleman J, Liechti R, Bridge A, Sandström J, Jaquet V, Xenarios I, Krause KH
bioRxiv, 17 Jan 2018
Contrast-induced nephropathy: Basic concepts, pathophysiological implications and prevention strategies
Mamoulakis C, Tsarouhas K, Fragkiadoulaki I, Heretis I, Wilks MF, Spandidos DA, Tsitsimpikou C, Tsatsakis A
Pharmacology & Therapeutics, 31 Déc 2017
Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study
Randazzo GM, Tonoli D, Strajhar P, Xenarios I, Odermatt A, Boccard J, Rudaz S
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 15 Déc 2017
ART, Stoffenmanager, and TRA: A Systematic Comparison of Exposure Estimates Using the TREXMO Translation System
Savic N, Gasic B, Vernez D
Annals of Work Exposures and Health, 15 Déc 2017