Publications

Hepatocellular toxicity of benzbromarone: Effects on mitochondrial function and structure

Felser A, Lindinger PW, Schnell D, Kratschmar DV, Odermatt A, Mies S, Jenö P, Krähenbühl S

Toxicology,  3 Oct 2014


Geneva cocktail for cytochrome P450 and P-glycoprotein activity assessment using dried blood spot

Bosilkovska M, Samer CF, Déglon J, Rebsamen M, Staub C, Dayer P, Walder B, Desmeules JA, Daali Y

Clinical Pharmacology and Therapeutics,  30 Sep 2014


Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice

Tao J, Calvisi DF, Ranganathan S, Cigliano A, Zhou L, Singh S, Jiang L, Fan B, Terracciano L, Armeanu-Ebinger S, Ribback S, Dombrowski F, Evert M, Chen X, Monga SP

Gastroenterology,  30 Sep 2014


Repeated exposure to Ochratoxin A generates a neuroinflammatory response, characterized by neurodegenerative M1 microglial phenotype

von Tobel JS, Antinori P, Zurich MG, Rosset R, Aschner M, Glück F, Scherl A, Monnet-Tschudi F

Neurotoxicology,  30 Sep 2014


Using pluripotent stem cells and their progeny as an in vitro model to assess (developmental) neurotoxicity

Hoelting L, Leist M, Stoppini L

Methods and Principles in Medicinal Chemistry: "Predictive Toxicology - From Vision to Reality" (Eds. Pfannkuch F. and Suter-Dick L.), Vol 64. Wiley-VCH Publisher,  26 Sep 2014


Establishment of rodent and human in vitro systems for the investigation of testicular toxicity

Gastaldello A, Escoffier J, Kustermann S, Clemann N, Nef S, Stoppini L

Toxicology Letters,  10 Sep 2014


Hepatic toxicity of dronedarone in mice: Role of mitochondrial β-oxidation

Felser A, Stoller A, Morand R, Schnell D, Donzelli M, Terracciano L, Bouitbir J, Krähenbühl S

Toxicology,  2 Sep 2014


Phenotyping of CYP450 in human liver microsomes using the cocktail approach

Spaggiari D, Geiser L, Daali Y, Rudaz S

Analytical and Bioanalytical Chemistry,  31 Aoû 2014


Seizures after single-agent overdose with pharmaceutical drugs: Analysis of cases reported to a poison center

Reichert C, Reichert P, Monnet-Tschudi F, Kupferschmidt H, Ceschi A, Rauber-Lüthy C

Clinical Toxicology,  31 Jul 2014


Ligand-based pharmacophore modeling and virtual screening for the discovery of novel 17β-hydroxysteroid dehydrogenase 2 inhibitors

Vuorinen A, Engeli R, Meyer A, Bachmann F, Griesser UJ, Schuster D, Odermatt A

Journal of Medicinal Chemistry,  24 Jul 2014