Recent Publications

Effect of the catechol-O-methyltransferase inhibitors tolcapone and entacapone on fatty acid metabolism in HepaRG cells [Epub ahead of print]

Felser A
Duthaler U
Toxicological Sciences
23/04/2018

Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells

Frontiers in Pharmacology
23/04/2018

Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines

Journal of Applied Toxicology
31/03/2018

Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis

Heliyon
28/02/2018

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity [Epub ahead of print]

Bal-Price A
Hogberg HT
Crofton KM
Daneshian M
Fritsche E
Heinonen T
Hougaard Bennekou S
Klima S
Piersma AH
Sachana M
Shafer TJ
Terron A
Monnet-Tschudi F
Viviani B
Waldmann T
Westerink RHS
Witters H
Zurich MG
Leist M
ALTEX
23/02/2018

Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells

Toxicology
15/02/2018

An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition

Terron A
Bal-Price A
Paini A
Monnet-Tschudi F
Bennekou SH
EFSA WG EPI1 Members
Leist M
Schildknecht S
Archives of Toxicology
31/01/2018

Navigating in vitro bioactivity data: investigating available resources using model compounds

Ilmjarv S
Augsburger F
Tjalling Bolleman J
Liechti R
Bridge A
Jaquet V
Xenarios I
bioRxiv
17/01/2018

Contrast-induced nephropathy: Basic concepts, pathophysiological implications and prevention strategies

Mamoulakis C
Tsarouhas K
Fragkiadoulaki I
Heretis I
Spandidos DA
Tsitsimpikou C
Tsatsakis A
Pharmacology & Therapeutics
31/12/2017

Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study

Tonoli D
Strajhar P
Xenarios I
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
15/12/2017