Publications

Zebrafish as a model to assess the neurotoxic potential of propylene glycol ethers

Puligilla RD, Roos NJ, Bolten SJ, Hopf NB, Zurich M-G, Barulin N, Huwyler J

Environmental toxicology and pharmacology,  1 Jun 2025


Multi-behavioral phenotyping in early-life-stage zebrafish for identifying disruptors of non-associative learning [online ahead of print]

Leuthold D, Herold NK, Nerlich J, Bartmann K, Scharkin I, Hallermann SJ, Schweiger N, Fritsche E, Tal T

Environmental Health Perspectives,  30 May 2025


A comparative study of biostatistical pipelines for benchmark concentration modeling of in vitro screening assays [online ahead of print]

Carstens KE, Dönmez A, Hsieh J-H, Bartmann K, Friedman KP, Koch K, Scholze M, Fritsche E

Computational Toxicology,  30 May 2025


Panel discussions on the global regulatory acceptance and harmonisation of non-animal NAMs

Courtot L, Fritsche E, Hobi N, Kleinstreuer N, Lee R, Parvatam S, Ritskes-Hoitinga M, Roper C, Westmoreland C, Gougeon E

NAM Journal,  24 May 2025


2024 International Academy of Toxicologic Pathology (IATP) Satellite Symposium: New Approach Methodologies (NAMs) for Neurotoxicity Assessment and Regulatory Perspectives [online ahead of print]

Hogberg HT, Fritsche E, Gröters S, Kovi RC, Rao DB, Terron A, Winter MJ

Toxicologic Pathology,  15 May 2025


Developmental neurotoxicity as a case example for a six-step framework for the sustainable regulatory implementation of NAMs [online ahead of print]

Blum J, Bartmann K, de Paula Souza J, Fritsche E

Current Opinion in Toxicology,  2 May 2025


Application of a high-density microelectrode array assay using a 3D human iPSC-derived brain microphysiological system model for in vitro neurotoxicity screening of environmental compounds [online ahead of print]

Carstens KE, Gronskaya E, Jäckel D, Bertoli J, Ramirez Cuevas K, Dorier J, Wang S, Lopez-Rodriguez D, Shafer TJ, Zurich M-G, Pamies D

Archives of Toxicology,  28 Apr 2025


Nuclear hormone receptors control fundamental processes of human fetal neurodevelopment: Basis for endocrine disruption assessment [online ahead of print]

Koch K, Schlüppmann K, Hüsken S, Stark LM, Förster, Masjosthusmann S, Klose J, Dönmez A, Fritsche E

Environmental International,  20 Mar 2025


Hepatic and Extra-Hepatic Metabolism of Propylene Glycol Ethers in the Context of Central Nervous System Toxicity [online ahead of print]

Werner S, Pamies D, Zurich MG, Suter-Dick L

Toxicology,  8 Feb 2025


New approach methodologies in human health risk assessment across European regulatory frameworks: Status quo, barriers and drivers for regulatory acceptance and use

Bearth A, Roth N, Jansen T, Holden L, Čavoški A, Di Consiglio E, Hauzenberger I, Lee R, Mombelli E, Tcheremenskaia O, Wendt-Rasch L, Wilks MF

Environment International,  1 Feb 2025