Publications
Bridging AI Advancements with Risk Assessment Needs: A Journey Towards Effective Use and Regulatory Acceptance
Kolesnyk S. , De Paula Souza J., Bearth A., Aicher L., Wilks M.F., Mosig A., Fritsche E.
Toxicology, 1 Jun 2026
Regulation of chemicals demands assessment of risks rather than identification of hazards only
Marx-Stoelting P, Ritz V, Herzler M, Kneuer C, Aiello-Holden K, Brescia S, Escher SE, Feustel S, Fritsche E, Gebel J, Kenny EF, Landsiedel R, Sanders P, Schwarz M, Streitz M, Testai E, van Ravenzwaay B, Waetjen W, Wend K, Wilks M, Luch A, Tralau T, Hensel A.
Archives of Toxicology, 7 Feb 2026
Exploring experiences of the regulatory toxicology system: system‑level promoters and inhibitors of new approach methodologies
Bearth A, Kopainsky B, Jones LB, Vist, G., Husøy, T, Svendsen C, Whaley P, Hoffmann S,· Ames HM, Solstad G, Bloch D, Čavoški A, Chiu WA, Davenport D, Davies HG, Giusti A, Hartung T, Kwon S, Osborne OJ, Rooney AA, Rousselle C, Sass JB, Wright FA, Mathisen GH
Archives of Toxicology, 18 Aug 2025
Zebrafish as a model to assess the neurotoxic potential of propylene glycol ethers
Puligilla RD, Roos NJ, Bolten SJ, Hopf NB, Zurich M-G, Barulin N, Huwyler J
Environmental toxicology and pharmacology, 1 Jun 2025
A comparative study of biostatistical pipelines for benchmark concentration modeling of in vitro screening assays [online ahead of print]
Carstens KE, Dönmez A, Hsieh J-H, Bartmann K, Friedman KP, Koch K, Scholze M, Fritsche E
Computational Toxicology, 30 May 2025
Multi-behavioral phenotyping in early-life-stage zebrafish for identifying disruptors of non-associative learning [online ahead of print]
Leuthold D, Herold NK, Nerlich J, Bartmann K, Scharkin I, Hallermann SJ, Schweiger N, Fritsche E, Tal T
Environmental Health Perspectives, 30 May 2025
Panel discussions on the global regulatory acceptance and harmonisation of non-animal NAMs
Courtot L, Fritsche E, Hobi N, Kleinstreuer N, Lee R, Parvatam S, Ritskes-Hoitinga M, Roper C, Westmoreland C, Gougeon E
NAM Journal, 24 May 2025
2024 International Academy of Toxicologic Pathology (IATP) Satellite Symposium: New Approach Methodologies (NAMs) for Neurotoxicity Assessment and Regulatory Perspectives [online ahead of print]
Hogberg HT, Fritsche E, Gröters S, Kovi RC, Rao DB, Terron A, Winter MJ
Toxicologic Pathology, 15 May 2025
Developmental neurotoxicity as a case example for a six-step framework for the sustainable regulatory implementation of NAMs [online ahead of print]
Blum J, Bartmann K, de Paula Souza J, Fritsche E
Current Opinion in Toxicology, 2 May 2025
New approach methodologies in human health risk assessment across European regulatory frameworks: Status quo, barriers and drivers for regulatory acceptance and use
Bearth A, Roth N, Jansen T, Holden L, Čavoški A, Di Consiglio E, Hauzenberger I, Lee R, Mombelli E, Tcheremenskaia O, Wendt-Rasch L, Wilks MF
Environment International, 1 Feb 2025