Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo

Bonifacio A, Mullen PJ, Mityko IS, Navegantes LC, Bouitbir J, Krähenbühl S

Archives of Toxicology,  31 Jan 2016

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Longitudinal monitoring of endogenous steroids in human serum by UHPLC-MS/MS as a tool to detect testosterone abuse in sports

Ponzetto F, Mehl F, Boccard J, Baume N, Rudaz S, Saugy M, Nicoli R

Analytical and Bioanalytical Chemistry,  31 Jan 2016

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Evaluation of steroidomics by liquid chromatography hyphenated to mass spectrometry as a powerful analytical strategy for measuring human steroid perturbations

Jeanneret F, Tonoli D, Rossier MF, Saugy M, Boccard J, Rudaz S

Journal of Chromatography,  22 Jan 2016

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Statins Trigger Mitochondrial Reactive Oxygen Species-Induced Apoptosis in Glycolytic Skeletal Muscle

Bouitbir J, Singh F, Charles AL, Schlagowski AI, Bonifacio A, Echaniz-Laguna A, Geny B, Krähenbühl S, Zoll J

Antioxidants & Redox Signaling,  10 Jan 2016

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Evaluation and identification of dioxin exposure biomarkers in human urine by high-resolution metabolomics, multivariate analysis and in vitro synthesis

Jeanneret F, Tonoli D, Hochstrasser D, Saurat JH, Sorg O, Boccard J, Rudaz S

Toxicology Letters,  5 Jan 2016

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Presentations to the Emergency Department Following Cannabis use—a Multi-Centre Case Series from Ten European Countries

Dines AM, Wood DM, Galicia M, Yates CM, Heyerdahl F, Hovda KE, Giraudon I, Sedefov R, Euro-DEN Research Group, Dargan PI

Journal of Medical Toxicology,  31 Dec 2015

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Comparative safety evaluation of silica-based particles

Kettiger H, Sen Karaman D, Schiesser L, Rosenholm JM, Huwyler J

Toxicology In Vitro,  25 Dec 2015

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Cell type-specific expression and localization of cytochrome P450 isoforms in tridimensional aggregating rat brain cell cultures

Vichi S, Sandström von Tobel J, Gemma S, Stanzel S, Kopp-Schneider A, Monnet-Tschudi F, Testai E, Zurich MG

Toxicology In Vitro,  25 Dec 2015

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Pharmacophore Models and Pharmacophore-Based Virtual Screening: Concepts and Applications Exemplified on Hydroxysteroid Dehydrogenases

Kaserer T, Beck KR, Akram M, Odermatt A, Schuster D

Molecules,  19 Dec 2015

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Swiss University Students' Attitudes toward Pharmacological Cognitive Enhancement

Maier LJ, Liakoni E, Schildmann J, Schaub MP, Liechti ME

PLoS One,  10 Dec 2015