Publications
New approach methodologies in human health risk assessment across European regulatory frameworks: Status quo, barriers and drivers for regulatory acceptance and use
Bearth A, Roth N, Jansen T, Holden L, Čavoški A, Di Consiglio E, Hauzenberger I, Lee R, Mombelli E, Tcheremenskaia O, Wendt-Rasch L, Wilks MF
Environment International, 1 Feb 2025
Editorial: Five grand challenges in toxicology
Fadeel B, Alexander J, Antunes SC, Dalhoff K, Fritsche E, Hogberg HT, Huaux F, Oredsson S, Pietroiusti A, Svingen T, Wilks MF
Frontiers in Toxicology, 21 Jan 2025
The long way from raw data to NAM-based information: Overview on data layers and processing steps
Blum J, Brüll M, Hengstler JG, Dietrich DR, Gruber AJ, Dipalo M, Kraushaar U, Mangas I, Terron A, Fritsche E, Marx-Stoelting P, Hardy B, Schepky A, Escher S, Hartung T, Landsiedel R, Odermatt A, Sachana M, Koch K, Dönmez A, Masjosthusmann S, Bothe K, Schildknecht S, Beilmann M, Beltman JB, Fitzpatrick S, Mangerich A, Rehm M, Tangianu S, Zickgraf FM, Kamp H, Burger G, van de Water B, Kleinstreuer N, White A, Leist M
ALTEX, 14 Jan 2025
State of the science on assessing developmental neurotoxicity using new approach methods [online ahead of print]
Debad SJ, Aungst J, Carstens K, Ferrer M, Fitzpatrick S, Fritsche E, Geng Y, Hartung T, Hogberg HT, Li R, Mangas I, Marty S, Musser S, Perron M, Rattan S, Rüegg J, Sachana M, Schenke M, Shafer TJ, Smirnova L, Talpos J, Tanguay RL, Terron A, Bandele O
ALTEX, 9 Dec 2024
Transcriptomic characterization of 2D and 3D human induced pluripotent stem cell-based in vitro models as New Approach Methodologies for developmental neurotoxicity testing [online ahead of print]
Lislien M, Kuchovska E, Kapr J, Duale N, Andersen JM, Dirven H, Myhre O, Fritsche E, Koch K, Wojewodzic MW
Toxicology, 15 Nov 2024
International STakeholder NETwork (ISTNET) Workshop for creating a developmental and reproductive toxicity (DART) testing roadmap for regulatory purposes
Fritsche E, Aspiroz LS, Arand M, Faustman E, Müller I
ALTEX, 22 Oct 2024
New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project
Tal T, Myhre O, Fritsche E, Rüegg J, Craenen K, Aiello-Holden K, Agrillo C, Babin PJ, Escher BI, Dirven H, Hellsten K, Dolva K, Hessel E, Heusinkveld HJ, Hadzhiev Y, Hurem A, Jagiello K, Judzinska B, Klüver N, Knoll-Gellida A, Kühne BA, Leist M, Lislien M, Lyche JL, Müller F, Colbourne JK, Neuhaus W, Pallocca G, Seeger B, Scharkin I, Scholz S, Spjuth O, Torres-Ruiz M, Bartmann K
Frontiers in Toxicology, 26 Apr 2024
Intuitive toxicology in the 21st century-Bridging the perspectives of the public and risk assessors in Europe [online ahead of print]
Bearth A, Roth N, Wilks MF, Siegrist M
Risk Analysis, 15 Mar 2024
The Clinical Toxicology Recommendations Collaborative: purpose, organization, and methodology [online ahead of print]
Wilks MF, Hoyte C, Cumpston KL, Hassanian-Moghaddam H, Tse ML, Ferrer-Dufol A, Thiermann H
Clinical Toxicology, 11 Mar 2024
Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps
Jaylet T, Coustillet T, Smith NM, Viviani B, Lindeman B, Vergauwen L, Myhre O, Yarar N, Gostner JM, Monfort-Lanzas P, Jornod F, Holbech H, Coumoul X, Sarigiannis DA, Antczak P, Bal-Price A, Fritsche E, Kuchovska E, Stratidakis AK, Barouki R, Kim MJ, Taboureau O, Wojewodzic MW, Knapen D, Audouze K
Frontiers in Toxicology, 8 Mar 2024