Publications

Systems Toxicology: Real World Applications and Opportunities

Hartung T, FitzGerald RE, Jennings P, Mirams GR, Peitsch MC, Rostami-Hodjegan A, Shah I, Wilks MF, Sturla SJ

Chemical Research in Toxicology,  17 Apr 2017


Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids

Strajhar P, Tonoli D, Jeanneret F, Imhof RM, Malagnino V, Patt M, Kratschmar DV, Boccard J, Rudaz S, Odermatt A

Toxicology,  15 Apr 2017


Inhibition of 11β-hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole

Beck KR, Bächler M, Vuorinen A, Wagner S, Akram M, Griesser U, Temml V, Klusonova P, Yamaguchi H, Schuster D, Odermatt A

Biochemical Pharmacology,  15 Apr 2017


Development and characterization of a human embryonic stem cell-derived 3D neural tissue model for neurotoxicity testing

Sandström J, Eggermann E, Charvet I, Roux A, Toni N, Greggio C, Broyer A, Monnet-Tschudi F, Stoppini L

Toxicology In Vitro,  28 Feb 2017


Metabolomic analysis of urine samples by UHPLC-QTOF-MS: Impact of normalization strategies

Gagnebin Y, Tonoli D, Lescuyer P, Ponte B, de Seigneux S, Martin PY, Schappler J, Boccard J, Rudaz S

Analytica Chimica Acta,  22 Feb 2017


Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay

Colaianna M, Ilmjärv S, Peterson H, Kern I, Julien S, Baquié M, Pallocca G, Bosgra S, Sachinidis A, Hengstler JG, Leist M, Krause KH

Archives of Toxicology,  31 Jan 2017


Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice

Haegler P, Grünig D, Berger B, Terracciano L, Krähenbühl S, Bouitbir J

PLoS One,  30 Jan 2017


Indirect Quantitative Structure-Retention Relationship for Steroid Identification: A chemometric challenge at “Chimiométrie 2016”

Randazzo GM, Vigneau E, Courcoux P, Harrouet C, Lijour Y, Dardenne P, Boccard J, Rudaz S

Chemometrics and Intelligent Laboratory Systems, Volume 160, Pages 52-58,  15 Jan 2017


Testicular Dysgenesis Syndrome and Long-Lasting Epigenetic Silencing of Mouse Sperm Genes Involved in the Reproductive System after Prenatal Exposure to DEHP

Stenz L, Escoffier J, Rahban R, Nef S, Paoloni-Giacobino A

PLoS One,  13 Jan 2017


Tollip, an early regulator of the acute inflammatory response in the substantia nigra

Humbert-Claude M, Duc D, Dwir D, Thieren L, Sandström von Tobel J, Begka C, Legueux F, Velin D, Maillard MH, Do KQ, Monnet-Tschudi F, Tenenbaum L

Journal of Neuroinflammation,  7 Dec 2016