Intuitive toxicology in the 21st century-Bridging the perspectives of the public and risk assessors in Europe [online ahead of print]

Bearth A, Roth N, Wilks MF, Siegrist M

Risk Analysis,  15 Mar 2024

The Clinical Toxicology Recommendations Collaborative: purpose, organization, and methodology [online ahead of print]

Wilks MF, Hoyte C, Cumpston KL, Hassanian-Moghaddam H, Tse ML, Ferrer-Dufol A, Thiermann H

Clinical Toxicology,  11 Mar 2024

Comprehensive mapping of the AOP-Wiki database: identifying biological and disease gaps

Jaylet T, Coustillet T, Smith NM, Viviani B, Lindeman B, Vergauwen L, Myhre O, Yarar N, Gostner JM, Monfort-Lanzas P, Jornod F, Holbech H, Coumoul X, Sarigiannis DA, Antczak P, Bal-Price A, Fritsche E, Kuchovska E, Stratidakis AK, Barouki R, Kim MJ, Taboureau O, Wojewodzic MW, Knapen D, Audouze K

Frontiers in Toxicology,  8 Mar 2024

Novel Strategy to Assess the Neurotoxicity of Organic Solvents Such as Glycol Ethers: Protocol for Combining In Vitro and In Silico Methods With Human-Controlled Exposure Experiments

Hopf NB, Suter-Dick L, Huwyler J, Borgatta M, Hegg L, Pamies D, Paschoud H, Puligilla RD, Reale E, Werner S, Zurich MG

JMIR Research Protocols,  18 Jan 2024

Taking the leap toward human-specific nonanimal methodologies: The need for harmonizing global policies for microphysiological systems

Parvatam S, Pamies D, Pistollato F, Beken S, Mariappan I, Roth A, Piergiovanni M, Maisonneuve BGC, Ewart L, Majumder A, Dandekar P, Date R, Mahadik K, Thiyagarajan S, Coecke S

Stem Cell Reports,  9 Jan 2024

Repeated Human Exposure to Semivolatile Organic Compounds by Inhalation: Novel Protocol for a Nonrandomized Study

Reale E, Hopf NB, Breider F, Grandjean D, Pirard C, Charlier C, Koch HM, Berthet A, Suarez G, Borgatta M

JMIR Research Protocols,  10 Oct 2023

Virtual screening and biological evaluation to identify pharmaceuticals potentially causing hypertension and hypokalemia by inhibiting steroid 11β-hydroxylase [online ahead of print]

Jäger MC, Kędzierski J, Gell V, Wey T, Kollár J, Winter DV, Schuster D, Smieško M, Odermatt A

Toxicology and Applied Pharmacology,  15 Sep 2023

Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone

Nunes C, Proença S, Ambrosini G, Pamies D, Thomas A, Kramer NI, Zurich MG

Frontiers in Pharmacology,  6 Sep 2023

Protocol for designing INVITES-IN, a tool for assessing the internal validity of in vitro studies

Svendsen C, Whaley P, Vist GE, Husøy, Beronius A, Di Consiglio E, Druwe I, Hartung T, Hatzi VI, Hoffmann S, Hooijmans CR, Machera K, Robinson JF, Roggen E, Rooney AA, Roth N, Spilioti E, Spyropoulou A, Tcheremenskaia O, Testai E, Vinken M, Mathisen GH

Evidence-Based Toxicology,  31 Aug 2023

Characterization of the interferences of systemic azole antifungal drugs with adrenal steroid biosynthesis using H295R cells and enzyme activity assays

Jäger MC, Joos FL, Winter DV, Odermatt A

Current Research in Toxicology,  14 Aug 2023