Publications

Exogenous Iron Increases Fasciocidal Activity and Hepatocellular Toxicity of the Synthetic Endoperoxides OZ78 and MT04

Brecht K, Kirchhofer C, Bouitbir J, Trapani F, Keiser J, Krähenbühl S

International Journal of Molecular Sciences,  1 Oct 2019


Toxicity of metamizole on differentiating HL60 cells and human neutrophil granulocytes

Rudin D, Roos NJ, Duthaler U, Krähenbühl S

Toxicology,  1 Oct 2019


Mitochondrial oxidative stress plays a critical role in the cardiotoxicity of sunitinib: Running title: Sunitinib and oxidative stress in hearts

Bouitbir J, Alshaikhali A, Panajatovic MV, Abegg VF, Paech F, Krähenbühl S

Toxicology,  1 Oct 2019


Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase

Akram M, Patt M, Kaserer T, Temml V, Waratchareeyakul W, Kratschmar DV, Haupenthal J, Hartmann RW, Odermatt A, Schuster D

The Journal of Steroid Biochemistry and Molecular Biology,  30 Sep 2019


11β-hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor gamma

Beck KR, Inderbinen SG, Kanagaratnam S, Kratschmar DV, Jetten AM, Yamaguchi H, Odermatt A

Journal of Lipid Research,  30 Sep 2019


Model-based estimation of lowest observed effect concentration from replicate experiments to identify potential biomarkers of in vitro neurotoxicity

Calderazzo S, Tavel D, Zurich MG, Kopp-Schneider A

Archives of Toxicology,  30 Sep 2019


In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice

Sandström J, Kratschmar DV, Broyer A, Poirot O, Marbet P, Chantong B, Zufferey F, Dos Santos T, Boccard J, Chrast R, Odermatt A, Monnet-Tschudi F

Archives of Toxicology,  30 Sep 2019


Accuracy, discriminative properties and reliability of a human ESC-based in vitro toxicity assay to distinguish teratogens responsible for neural tube defects

Feutz AC, De Geyter C

Archives of Toxicology,  31 Aug 2019


Mechanisms of insulin resistance by simvastatin in C2C12 myotubes and in mouse skeletal muscle

Sanvee GM, Panajatovic MV, Bouitbir J, Krähenbühl S

Biochemical Pharmacology,  30 Jun 2019


Drug-induced endocrine blood pressure elevation [Epub ahead of print]

Beck KR, Thompson GR, Odermatt A

Pharmacological Research,  15 Jun 2019