Publications
Novel Strategy to Assess the Neurotoxicity of Organic Solvents Such as Glycol Ethers: Protocol for Combining In Vitro and In Silico Methods With Human-Controlled Exposure Experiments
Hopf NB, Suter-Dick L, Huwyler J, Borgatta M, Hegg L, Pamies D, Paschoud H, Puligilla RD, Reale E, Werner S, Zurich MG
JMIR Research Protocols, 18 Jan 2024
Taking the leap toward human-specific nonanimal methodologies: The need for harmonizing global policies for microphysiological systems
Parvatam S, Pamies D, Pistollato F, Beken S, Mariappan I, Roth A, Piergiovanni M, Maisonneuve BGC, Ewart L, Majumder A, Dandekar P, Date R, Mahadik K, Thiyagarajan S, Coecke S
Stem Cell Reports, 9 Jan 2024
Repeated Human Exposure to Semivolatile Organic Compounds by Inhalation: Novel Protocol for a Nonrandomized Study
Reale E, Hopf NB, Breider F, Grandjean D, Pirard C, Charlier C, Koch HM, Berthet A, Suarez G, Borgatta M
JMIR Research Protocols, 10 Oct 2023
Virtual screening and biological evaluation to identify pharmaceuticals potentially causing hypertension and hypokalemia by inhibiting steroid 11β-hydroxylase [online ahead of print]
Jäger MC, Kędzierski J, Gell V, Wey T, Kollár J, Winter DV, Schuster D, Smieško M, Odermatt A
Toxicology and Applied Pharmacology, 15 Sep 2023
Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone
Nunes C, Proença S, Ambrosini G, Pamies D, Thomas A, Kramer NI, Zurich MG
Frontiers in Pharmacology, 6 Sep 2023
Protocol for designing INVITES-IN, a tool for assessing the internal validity of in vitro studies
Svendsen C, Whaley P, Vist GE, Husøy, Beronius A, Di Consiglio E, Druwe I, Hartung T, Hatzi VI, Hoffmann S, Hooijmans CR, Machera K, Robinson JF, Roggen E, Rooney AA, Roth N, Spilioti E, Spyropoulou A, Tcheremenskaia O, Testai E, Vinken M, Mathisen GH
Evidence-Based Toxicology, 31 Aug 2023
Characterization of the interferences of systemic azole antifungal drugs with adrenal steroid biosynthesis using H295R cells and enzyme activity assays
Jäger MC, Joos FL, Winter DV, Odermatt A
Current Research in Toxicology, 14 Aug 2023
Assessment of the inhibitory potential of anabolic steroids towards human AKR1D1 by computational methods and in vitro evaluation
Kędzierski J , Allard JA, Odermatt A, Smieško M
Toxicology Letters, 1 Aug 2023
The action of physiological and synthetic steroids on the calcium channel CatSper in human sperm
Wehrli L, Galdadas I, Voirol L, Smiesko M, Cambet Y, Jaquet V, Guerrier S, Gervasio FL, Nef S, Rahban R
Frontiers in Cell and Developmental Biology, 20 Jul 2023
Evaluating the food safety and risk assessment evidence-base of polyethylene terephthalate oligomers: A systematic evidence map
Schreier VN, Çörek E, Appenzeller-Herzog C, Brüschweiler BJ, Geueke B, Wilks MF, Schilter B, Muncke J, Simat TJ, Smieško M, Roth N, Odermatt A
Environment International, 30 Jun 2023