Publications

Profiling the proteomic inflammatory state of human astrocytes using DIA mass spectrometry

Dozio V, Sanchez JC

Journal of Neuroinflammation,  30 Nov 2018


Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice

Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S

Toxicology,  1 Nov 2018


A quantitative risk assessment for skin sensitizing plant protection products: Linking derived No-Effect levels (DNELs) with agricultural exposure models

Sanvido O, Schmid K, FitzGerald RE, Roth N, Wilks MF, Bormann P, Hopf NB

Regulatory Toxicology and Pharmacology,  31 Oct 2018


Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites

Marsousi N, Daali Y, Fontana P, Reny JL, Ancrenaz-Sirot V, Calmy A, Rudaz S, Desmeules JA, Samer CF

Clinical Pharmacokinetics,  31 Oct 2018


Longitudinal investigation of the metabolome of 3D aggregating brain cell cultures at different maturation stages by 1H HR-MAS NMR

Diserens G, Vermathen M, Zurich MG, Vermathen P

Analytical and Bioanalytical Chemistry,  31 Oct 2018


Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

Fritsche E, Grandjean P, Crofton KM, Aschner M, Goldberg A, Heinonen T, Hessel EVS, Hogberg HT, Bennekou SH, Lein PJ, Leist M, Mundy WR, Paparella M, Piersma AH, Sachana M, Schmuck G, Solecki R, Terron A, Monnet-Tschudi F, Wilks MF, Witters H, Zurich MG, Bal-Price A

Toxicology and Applied Pharmacology,  1 Sep 2018


Effect of the catechol-O-methyltransferase inhibitors tolcapone and entacapone on fatty acid metabolism in HepaRG cells

Grünig D, Felser A, Duthaler U, Bouitbir J, Krähenbühl S

Toxicological Sciences,  1 Aug 2018


High-dose immunosuppression to prevent death after paraquat self-poisoning - a randomised controlled trial

Gawarammana I, Buckley NA, Mohamed F, Naser K, Jeganathan K, Ariyananada PL, Wunnapuk K, Dobbins TA, Tomenson JA, Wilks MF, Eddleston M, Dawson AH

Clinical Toxicology (Phila),  31 Jul 2018


Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug

Berger B, Bachmann F, Duthaler U, Krähenbühl S, Haschke M

Frontiers in Pharmacology,  24 Jul 2018


Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity

Bal-Price A, Hogberg HT, Crofton KM, Daneshian M, FitzGerald RE, Fritsche E, Heinonen T, Hougaard Bennekou S, Klima S, Piersma AH, Sachana M, Shafer TJ, Terron A, Monnet-Tschudi F, Viviani B, Waldmann T, Westerink RHS, Wilks MF, Witters H, Zurich MG, Leist M

ALTEX,  9 Jul 2018