Toxicity of metamizole on differentiating HL60 cells and human neutrophil granulocytes

Rudin D, Roos NJ, Duthaler U, Krähenbühl S

Toxicology,  1 Oct 2019

Model-based estimation of lowest observed effect concentration from replicate experiments to identify potential biomarkers of in vitro neurotoxicity

Calderazzo S, Tavel D, Zurich MG, Kopp-Schneider A

Archives of Toxicology,  30 Sep 2019

In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice

Sandström J, Kratschmar DV, Broyer A, Poirot O, Marbet P, Chantong B, Zufferey F, Dos Santos T, Boccard J, Chrast R, Odermatt A, Monnet-Tschudi F

Archives of Toxicology,  30 Sep 2019

11β-hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor gamma

Beck KR, Inderbinen SG, Kanagaratnam S, Kratschmar DV, Jetten AM, Yamaguchi H, Odermatt A

Journal of Lipid Research,  30 Sep 2019

Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase

Akram M, Patt M, Kaserer T, Temml V, Waratchareeyakul W, Kratschmar DV, Haupenthal J, Hartmann RW, Odermatt A, Schuster D

The Journal of Steroid Biochemistry and Molecular Biology,  30 Sep 2019

Accuracy, discriminative properties and reliability of a human ESC-based in vitro toxicity assay to distinguish teratogens responsible for neural tube defects

Feutz AC, De Geyter C

Archives of Toxicology,  31 Aug 2019

Mechanisms of insulin resistance by simvastatin in C2C12 myotubes and in mouse skeletal muscle

Sanvee GM, Panajatovic MV, Bouitbir J, Krähenbühl S

Biochemical Pharmacology,  30 Jun 2019

Genetic resistance to DEHP-induced transgenerational endocrine disruption

Stenz L, Rahban R, Prados J, Nef S, Paoloni-Giacobino A

PLoS One,  10 Jun 2019

Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2

Thompson GR, Beck KR, Patt M, Kratschmar DV, Odermatt A

Journal of the Endocrine Society,  6 Jun 2019

Non-immunological toxicological mechanisms of metamizole-associated neutropenia in HL60 cells

Rudin D, Lanzilotto A, Bachmann F, Housecroft CE, Constable EC, Drewe J, Haschke M, Krähenbühl S

Biochemical Pharmacology,  31 May 2019