Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study

Randazzo GM, Tonoli D, Strajhar P, Xenarios I, Odermatt A, Boccard J, Rudaz S

Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences,  15 Dec 2017

Unravelling the effects of multiple experimental factors in metabolomics, analysis of human neural cells with hydrophilic interaction liquid chromatography hyphenated to high resolution mass spectrometry

González-Ruiz V, Pezzatti J, Roux A, Stoppini L, Boccard J, Rudaz S

Journal of Chromatography. A.,  8 Dec 2017

Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072

Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, Krähenbühl S, Maurer M

Archives of Toxicology,  30 Nov 2017

PDMS-b-PMOXA polymersomes for hepatocyte targeting and assessment of toxicity

Kiene K, Schenk SH, Porta F, Ernst A, Witzigmann D, Grossen P, Huwyler J

European Journal of Pharmaceutics and Biopharmaceutics,  31 Oct 2017

Comparing the Advanced REACH Tool's (ART) Estimates With Switzerland's Occupational Exposure Data

Savic N, Gasic B, Schinkel J, Vernez D

Annals of Work Exposures and Health,  1 Oct 2017

Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases

Engeli RT, Rohrer SR, Vuorinen A, Herdlinger S, Kaserer T, Leugger S, Schuster D, Odermatt A

International Journal of Molecular Sciences,  19 Sep 2017

Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases

Romand S, Spaggiari D, Marsousi N, Samer C, Desmeules J, Daali Y, Rudaz S

Journal of Pharmaceutical and Biomedical Analysis,  10 Sep 2017

Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects

Dolder PC, Strajhar P, Vizeli P, Hammann F, Odermatt A, Liechti ME

Frontiers in Pharmacology,  7 Sep 2017

The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells

Grünig D, Felser A, Bouitbir J, Krähenbühl S

Toxicology in Vitro,  31 Aug 2017

Selective stimulation of the JAK/STAT signaling pathway by silica nanoparticles in human endothelial cells

Siegrist S, Kettiger H, Fasler-Kan E, Huwyler J

Toxicology In Vitro,  31 Aug 2017