In vitro models to study insulin and glucocorticoids modulation of trimethyltin (TMT)-induced neuroinflammation and neurodegeneration, and in vivo validation in db/db mice

Sandström J, Kratschmar DV, Broyer A, Poirot O, Marbet P, Chantong B, Zufferey F, Dos Santos T, Boccard J, Chrast R, Odermatt A, Monnet-Tschudi F

Archives of Toxicology,  30 Sep 2019

11β-hydroxysteroid dehydrogenases control access of 7β,27-dihydroxycholesterol to retinoid-related orphan receptor gamma

Beck KR, Inderbinen SG, Kanagaratnam S, Kratschmar DV, Jetten AM, Yamaguchi H, Odermatt A

Journal of Lipid Research,  30 Sep 2019

Model-based estimation of lowest observed effect concentration from replicate experiments to identify potential biomarkers of in vitro neurotoxicity

Calderazzo S, Tavel D, Zurich MG, Kopp-Schneider A

Archives of Toxicology,  30 Sep 2019

Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase

Akram M, Patt M, Kaserer T, Temml V, Waratchareeyakul W, Kratschmar DV, Haupenthal J, Hartmann RW, Odermatt A, Schuster D

The Journal of Steroid Biochemistry and Molecular Biology,  30 Sep 2019

Accuracy, discriminative properties and reliability of a human ESC-based in vitro toxicity assay to distinguish teratogens responsible for neural tube defects

Feutz AC, De Geyter C

Archives of Toxicology,  31 Aug 2019

Mechanisms of insulin resistance by simvastatin in C2C12 myotubes and in mouse skeletal muscle

Sanvee GM, Panajatovic MV, Bouitbir J, Krähenbühl S

Biochemical Pharmacology,  30 Jun 2019

Genetic resistance to DEHP-induced transgenerational endocrine disruption

Stenz L, Rahban R, Prados J, Nef S, Paoloni-Giacobino A

PLoS One,  10 Jun 2019

Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2

Thompson GR, Beck KR, Patt M, Kratschmar DV, Odermatt A

Journal of the Endocrine Society,  6 Jun 2019

Non-immunological toxicological mechanisms of metamizole-associated neutropenia in HL60 cells

Rudin D, Lanzilotto A, Bachmann F, Housecroft CE, Constable EC, Drewe J, Haschke M, Krähenbühl S

Biochemical Pharmacology,  31 May 2019

Semen quality of young men in Switzerland: a nationwide cross‐sectional population‐based study

Rahban R, Priskorn L, Senn A, Stettler E, Galli F, Vargas J, Van den Bergh M, Fusconi A, Garlantezec R, Jensen TK, Multigner L, Skakkebæk NE, Germond M, Jørgensen N, Nef S, NICER Working Group

Andrology,  21 May 2019