Publications

Editorial by Prof. Ellen Fritsche on PARCOPEDIA: "PARC plays a pivotal role in shaping the future of chemical risk assessment in Europe"

Ellen Fritsche

PARCOPEDIA,  25 Jul 2025


The Cost Outcome Pathway framework: Integrating socio-economic impacts to Adverse Outcome Pathways for supporting policy makers

Coustillet T, Bearth, A, Coumoul X, Villégier, A-S, Bisson M, Fritsche, E, Brignon, J-M, Zeman F, Audouze, K

Toxicology,  22 Jun 2025


Zebrafish as a model to assess the neurotoxic potential of propylene glycol ethers

Puligilla RD, Roos NJ, Bolten SJ, Hopf NB, Zurich M-G, Barulin N, Huwyler J

Environmental toxicology and pharmacology,  1 Jun 2025


A comparative study of biostatistical pipelines for benchmark concentration modeling of in vitro screening assays [online ahead of print]

Carstens KE, Dönmez A, Hsieh J-H, Bartmann K, Friedman KP, Koch K, Scholze M, Fritsche E

Computational Toxicology,  30 Mai 2025


Multi-behavioral phenotyping in early-life-stage zebrafish for identifying disruptors of non-associative learning [online ahead of print]

Leuthold D, Herold NK, Nerlich J, Bartmann K, Scharkin I, Hallermann SJ, Schweiger N, Fritsche E, Tal T

Environmental Health Perspectives,  30 Mai 2025


Panel discussions on the global regulatory acceptance and harmonisation of non-animal NAMs

Courtot L, Fritsche E, Hobi N, Kleinstreuer N, Lee R, Parvatam S, Ritskes-Hoitinga M, Roper C, Westmoreland C, Gougeon E

NAM Journal,  24 Mai 2025


2024 International Academy of Toxicologic Pathology (IATP) Satellite Symposium: New Approach Methodologies (NAMs) for Neurotoxicity Assessment and Regulatory Perspectives [online ahead of print]

Hogberg HT, Fritsche E, Gröters S, Kovi RC, Rao DB, Terron A, Winter MJ

Toxicologic Pathology,  15 Mai 2025


Developmental neurotoxicity as a case example for a six-step framework for the sustainable regulatory implementation of NAMs [online ahead of print]

Blum J, Bartmann K, de Paula Souza J, Fritsche E

Current Opinion in Toxicology,  2 Mai 2025


Application of a high-density microelectrode array assay using a 3D human iPSC-derived brain microphysiological system model for in vitro neurotoxicity screening of environmental compounds [online ahead of print]

Carstens KE, Gronskaya E, Jäckel D, Bertoli J, Ramirez Cuevas K, Dorier J, Wang S, Lopez-Rodriguez D, Shafer TJ, Zurich M-G, Pamies D

Archives of Toxicology,  28 Apr 2025


Nuclear hormone receptors control fundamental processes of human fetal neurodevelopment: Basis for endocrine disruption assessment [online ahead of print]

Koch K, Schlüppmann K, Hüsken S, Stark LM, Förster, Masjosthusmann S, Klose J, Dönmez A, Fritsche E

Environmental International,  20 Mär 2025