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Human ReN-derived astrocyte reactivity is associated with profound changes in cytoskeleton and increased glycolysis (photo: © MG Zurich laboratory, 2021)

Binding of itraconazole to human 11b-HSD2 (photo: © Martin Smiesko, Universität Basel, 2021)

Shedding light on biodistribution of metal-based nanoparticles in Zebrafish by computed tomography (photo: © Huwyler laboratory, 2020)

BrainSpheres: testing neurotoxicity in human cells (photo: © David Pamies, Univ. of Lausanne, 2020)

Wir beraten die Behörden, fördern angewandte Forschung und bieten Aus- und Weiterbildungen in der Humantoxikologie an

Regulatorische Toxikologie

Forschung

Ausbildung

Publications

In vivo safety testing of Antibody Drug Conjugates

Regulatory Toxicology and Pharmacology, 30 Jun 2021

Neuroinflammatory Response to TNFα and IL1β Cytokines Is Accompanied by an Increase in Glycolysis in Human Astrocytes In Vitro

International Journal of Molecular Sciences, 14 Apr 2021

Assessment of fibrotic pathways induced by environmental chemicals using 3D-human liver microtissue model

Environmental Research, 31 Mär 2021

Approaches in metabolomics for regulatory toxicology applications

The Analyst, 21 Mär 2021

Maternal occupational exposure to endocrine-disrupting chemicals during pregnancy and semen parameters in adulthood: results of a nationwide cross-sectional study among Swiss conscripts [online ahead of print]

Human Reproduction, 17 Mär 2021

The L1-dependant and Pol III transcribed Alu retrotransposon, from its discovery to innate immunity [online ahead of print]

Molecular Biology Reports, 16 Mär 2021

News

World's first toxicology testing strategy without animal testing adopted by OECD

22 Jul 2021

Call for research projects in applied human toxicology now open - Submission deadline 15 September 2021

30 Jun 2021

Latest 'OECD Chemical Safety and Biosafety Progress Report' released (issue no. 41)

25 Jun 2021

Events

EUROTOX 2021: 'Toxicology of the next generation – Combined efforts in the quest for safer chemicals and medicines'

Virtual meeting , 26 Sep – 1 Okt 2021

Karolinska AOP training: 'Adverse Outcome Pathways (AOPs) – principles and applications in toxicology and health risk assessment'

Online , 10 Okt – 15 Okt 2021

TEDD Annual Meeting 2021: 'Cross-industrial applications of organotypic models'

Wädenswil (Switzerland) , 14 Okt 2021

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