Publications

Scientific Opinion of the Scientific Panel on Plant Protection Products and their Residues (PPR Panel) on testing and interpretation of comparative in vitro metabolism studies

EFSA Panel on Plant Protection Products and their Residues (EFSA PPR Panel); Hernandez-Jerez AF, Adriaanse P, Aldrich A, Berny P, Coja T, Duquesne S, Focks A, Marinovich M, Millet M, Pelkonen O, Pieper S, Tiktak A, Topping CJ, Widenfalk A, Wilks M, Wolterink G, Gundert-Remy U, Louisse J, Rudaz S, Testai E, Lostia A, Dorne JL, Parra Morte JM

EFSA Journal,  23 Dez 2021


Modulation of 11β-hydroxysteroid dehydrogenase functions by the cloud of endogenous metabolites in a local microenvironment: the glycyrrhetinic acid-like factor (GALF) hypothesis

Morris DJ, Brem AS, Odermatt A

Journal of Steroid Biochemistry and Molecular Biology,  30 Nov 2021


Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology

Harrill JA, Viant MR, Yauk CL, Sachana M, Gant TW, Auerbach Scott S, Beger RD, Bouhifd M, O'Brien J, Burgoon L, Caiment F, Carpi D, Chen T, Chorley BN, Colbourne J, Corvi R, Debrauwer L, O'Donovan C, Ebbels TMD, Ekman DR, Faulhammer F, Gribaldo L, Hilton GM, Jones SP, Kende A, Lawson TN, Leite SB, Leonards PEG, Luijten M, Martin A, Moussa L, Rudaz S, Schmitz O, Sobanski T, Strauss V, Vaccari M, Vijay V, Weber RJM, Williams AJ, Williams A, Thomas RS, Whelan M

Regulatory Toxicology and Pharmacology,  31 Okt 2021


New insights into the conversion of electropherograms to the effective electrophoretic mobility scale

Codesido S, Drouin N, Ferre S, Schappler J, Rudaz S, González-Ruiz V

Electrophoresis,  31 Okt 2021


Development of the SciRAP Approach for Evaluating the Reliability and Relevance of in vitro Toxicity Data

Roth N, Zilliacus J, Beronius A

Frontiers in Toxicology - Regulatory Toxicology,  15 Okt 2021


Enhanced Stability and Bioactivity of Natural Anticancer Topoisomerase I Inhibitors through Cyclodextrin Complexation

González-Ruiz V, Cores Á, Martín-Cámara O, Orellana K, Cervera-Carrascón V, Michalska P, Olives AI, León R, Martín MA, Menéndez JC

Pharmaceutics,  3 Okt 2021


The antidepressant Sertraline inhibits CatSper Ca2+ channels in human sperm

Rahban R, Rehfeld A, Schiffer C, Brenker C, Egeberg Palme DL, Wang T, Lorenz J, Almstrup K, Skakkebaek NE, Strünker T, Nef S

Human Reproduction,  18 Sep 2021


Identification of miR-199a-5p, miR-214-3p and miR-99b-5p as Fibrosis-Specific Extracellular Biomarkers and Promoters of HSC Activation

Messner CJ, Schmidt S, Özkul D, Gaiser C, Terracciano L, Krähenbühl S, Suter-Dick L

International Journal of Molecular Sciences,  10 Sep 2021


Human IPSC-Derived Model to Study Myelin Disruption

Chesnut M, Paschoud H, Repond C, Smirnova L, Hartung T, Zurich MG, Hogberg HT, Pamies D

International Journal of Molecular Sciences,  31 Aug 2021


Human Oligodendrocytes and Myelin In Vitro to Evaluate Developmental Neurotoxicity

Chesnut M, Hartung T, Hogberg H, Pamies D

International Journal of Molecular Sciences,  25 Jul 2021