Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases

Romand S, Spaggiari D, Marsousi N, Samer C, Desmeules J, Daali Y, Rudaz S

Journal of Pharmaceutical and Biomedical Analysis,  10 Sep 2017

Pharmacokinetics and Pharmacodynamics of Lisdexamfetamine Compared with D-Amphetamine in Healthy Subjects

Dolder PC, Strajhar P, Vizeli P, Hammann F, Odermatt A, Liechti ME

Frontiers in Pharmacology,  7 Sep 2017

The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells

Grünig D, Felser A, Bouitbir J, Krähenbühl S

Toxicology in Vitro,  31 Aug 2017

Selective stimulation of the JAK/STAT signaling pathway by silica nanoparticles in human endothelial cells

Siegrist S, Kettiger H, Fasler-Kan E, Huwyler J

Toxicology In Vitro,  31 Aug 2017

Intoxication by gamma hydroxybutyrate and related analogues: Clinical characteristics and comparison between pure intoxication and that combined with other substances of abuse

Miró Ò, Galicia M, Dargan P, Dines AM, Giraudon I, Heyerdahl F, Hovda KE, Yates C, Wood DM, Euro-DEN Research Group

Toxicology Letters,  5 Aug 2017

Virtual screening applications in short-chain dehydrogenase/reductase research

Beck KR, Kaserer T, Schuster D, Odermatt A

The Journal of Steroid Biochemistry and Molecular Biology,  31 Jul 2017

Mechanisms of hepatocellular toxicity associated with new psychoactive synthetic cathinones

Luethi D, Liechti ME, Krähenbühl S

Toxicology,  15 Jul 2017

Pro-fibrotic compounds induce stellate cell activation, ECM-remodelling and Nrf2 activation in a human 3D-multicellular model of liver fibrosis

Prestigiacomo V, Weston A, Messner S, Lampart F, Suter-Dick L

PLoS One,  30 Jun 2017

Development of a New Extraction Device Based on Parallel-Electromembrane Extraction

Drouin N, Mandscheff JF, Rudaz S, Schappler J

Analytical Chemistry,  20 Jun 2017

Hepatocellular Toxicity Associated with Tyrosine Kinase Inhibitors: Mitochondrial Damage and Inhibition of Glycolysis

Paech F, Bouitbir J, Krähenbühl S

Frontiers in Pharmacology,  14 Jun 2017