Publications

Effect of the catechol-O-methyltransferase inhibitors tolcapone and entacapone on fatty acid metabolism in HepaRG cells

Grünig D, Felser A, Duthaler U, Bouitbir J, Krähenbühl S

Toxicological Sciences,  1 Aug 2018


High-dose immunosuppression to prevent death after paraquat self-poisoning - a randomised controlled trial

Gawarammana I, Buckley NA, Mohamed F, Naser K, Jeganathan K, Ariyananada PL, Wunnapuk K, Dobbins TA, Tomenson JA, Wilks MF, Eddleston M, Dawson AH

Clinical Toxicology (Phila),  31 Jul 2018


Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug

Berger B, Bachmann F, Duthaler U, Krähenbühl S, Haschke M

Frontiers in Pharmacology,  24 Jul 2018


Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity

Bal-Price A, Hogberg HT, Crofton KM, Daneshian M, FitzGerald RE, Fritsche E, Heinonen T, Hougaard Bennekou S, Klima S, Piersma AH, Sachana M, Shafer TJ, Terron A, Monnet-Tschudi F, Viviani B, Waldmann T, Westerink RHS, Wilks MF, Witters H, Zurich MG, Leist M

ALTEX,  9 Jul 2018


Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways

Villeneuve DL, Landesmann B, Allavena P, Ashley N, Bal-Price A, Corsini E, Halappanavar S, Hussell T, Laskin D, Lawrence T, Nikolic-Paterson D, Pallardy M, Paini A, Pieters R, Roth R, Tschudi-Monnet F

Toxicological Sciences,  1 Jun 2018


Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells

Grünig D, Duthaler U, Krähenbühl S

Frontiers in Pharmacology,  23 Apr 2018


Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines

Mingard C, Paech F, Bouitbir J, Krähenbühl S

Journal of Applied Toxicology,  31 Mär 2018


Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis

Engeli RT, Fürstenberger C, Kratschmar DV, Odermatt A

Heliyon,  28 Feb 2018


Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells

Paech F, Mingard C, Grünig D, Abegg VF, Bouitbir J, Krähenbühl S

Toxicology,  15 Feb 2018


An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition

Terron A, Bal-Price A, Paini A, Monnet-Tschudi F, Bennekou SH, EFSA WG EPI1 Members, Leist M, Schildknecht S

Archives of Toxicology,  31 Jan 2018