Publications

Preclinical hazard evaluation strategy for nanomedicines

Siegrist S, Cörek E, Detampel P, Sandström J, Wick P, Huwyler J

Nanotoxicology,  28 Feb 2019


Presentations to the emergency department with non-medical use of benzodiazepines and Z-drugs: profiling and relation to sales data

Lyphout C, Yates C, Margolin ZR, Dargan PI, Dines AM, Heyerdahl F, Hovda KE, Giraudon I, Bucher-Bartelson B, Green JL, Euro-DEN Research Group, Wood DM

European Journal of Clinical Pharmacology,  31 Jan 2019


Steroid profiles in both blood serum and seminal plasma are not correlated and do not reflect sperm quality: Study on the male reproductive health of fifty young Swiss men

Zufferey F, Rahban R, Garcia A, Gagnebin Y, Boccard J, Tonoli D, Jeanneret F, Stettler E, Senn A, Nef S, Rudaz S, Rossier MF

Clinical Biochemistry,  31 Dez 2018


Optimizing drug discovery by Investigative Toxicology: Current and future trends

Beilmann M, Boonen H, Czich A, Dear G, Hewitt P, Mow T, Newham P, Oinonen T, Pognan F, Roth A, Valentin JP, Van Goethem F, Weaver RJ, Birk B, Boyer S, Caloni F, Chen AE, Corvi R, Cronin MTD, Daneshian M, Ewart LC, FitzGerald RE, Hamilton GA, Hartung T, Kangas JD, Kramer NI, Leist M, Marx U, Polak S, Rovida C, Testai E, Van der Water B, Vulto P, Steger-Hartmann T

ALTEX,  20 Dez 2018


Profiling the proteomic inflammatory state of human astrocytes using DIA mass spectrometry

Dozio V, Sanchez JC

Journal of Neuroinflammation,  30 Nov 2018


Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice

Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S

Toxicology,  1 Nov 2018


Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites

Marsousi N, Daali Y, Fontana P, Reny JL, Ancrenaz-Sirot V, Calmy A, Rudaz S, Desmeules JA, Samer CF

Clinical Pharmacokinetics,  31 Okt 2018


A quantitative risk assessment for skin sensitizing plant protection products: Linking derived No-Effect levels (DNELs) with agricultural exposure models

Sanvido O, Schmid K, FitzGerald RE, Roth N, Wilks MF, Bormann P, Hopf NB

Regulatory Toxicology and Pharmacology,  31 Okt 2018


Longitudinal investigation of the metabolome of 3D aggregating brain cell cultures at different maturation stages by 1H HR-MAS NMR

Diserens G, Vermathen M, Zurich MG, Vermathen P

Analytical and Bioanalytical Chemistry,  31 Okt 2018


Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

Fritsche E, Grandjean P, Crofton KM, Aschner M, Goldberg A, Heinonen T, Hessel EVS, Hogberg HT, Bennekou SH, Lein PJ, Leist M, Mundy WR, Paparella M, Piersma AH, Sachana M, Schmuck G, Solecki R, Terron A, Monnet-Tschudi F, Wilks MF, Witters H, Zurich MG, Bal-Price A

Toxicology and Applied Pharmacology,  1 Sep 2018