Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software

Marsousi N, Desmeules JA, Rudaz S, Daali Y

Biopharmaceutics & Drug Disposition,  31 Jan 2018

Navigating in vitro bioactivity data: investigating available resources using model compounds

Ilmjarv S, Augsburger F, Tjalling Bolleman J, Liechti R, Bridge A, Sandström J, Jaquet V, Xenarios I, Krause KH

bioRxiv,  17 Jan 2018

Contrast-induced nephropathy: Basic concepts, pathophysiological implications and prevention strategies

Mamoulakis C, Tsarouhas K, Fragkiadoulaki I, Heretis I, Wilks MF, Spandidos DA, Tsitsimpikou C, Tsatsakis A

Pharmacology & Therapeutics,  31 Dez 2017

Enhanced metabolite annotation via dynamic retention time prediction: Steroidogenesis alterations as a case study

Randazzo GM, Tonoli D, Strajhar P, Xenarios I, Odermatt A, Boccard J, Rudaz S

Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences,  15 Dez 2017

ART, Stoffenmanager, and TRA: A Systematic Comparison of Exposure Estimates Using the TREXMO Translation System

Savic N, Gasic B, Vernez D

Annals of Work Exposures and Health,  15 Dez 2017

Unravelling the effects of multiple experimental factors in metabolomics, analysis of human neural cells with hydrophilic interaction liquid chromatography hyphenated to high resolution mass spectrometry

González-Ruiz V, Pezzatti J, Roux A, Stoppini L, Boccard J, Rudaz S

Journal of Chromatography. A.,  8 Dez 2017

Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072

Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, Krähenbühl S, Maurer M

Archives of Toxicology,  30 Nov 2017

PDMS-b-PMOXA polymersomes for hepatocyte targeting and assessment of toxicity

Kiene K, Schenk SH, Porta F, Ernst A, Witzigmann D, Grossen P, Huwyler J

European Journal of Pharmaceutics and Biopharmaceutics,  31 Okt 2017

Comparing the Advanced REACH Tool's (ART) Estimates With Switzerland's Occupational Exposure Data

Savic N, Gasic B, Schinkel J, Vernez D

Annals of Work Exposures and Health,  1 Okt 2017

Interference of Paraben Compounds with Estrogen Metabolism by Inhibition of 17β-Hydroxysteroid Dehydrogenases

Engeli RT, Rohrer SR, Vuorinen A, Herdlinger S, Kaserer T, Leugger S, Schuster D, Odermatt A

International Journal of Molecular Sciences,  19 Sep 2017