Publications
A quantitative risk assessment for skin sensitizing plant protection products: Linking derived No-Effect levels (DNELs) with agricultural exposure models
Sanvido O, Schmid K, FitzGerald RE, Roth N, Wilks MF, Bormann P, Hopf NB
Regulatory Toxicology and Pharmacology, 31 Okt 2018
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes
Fritsche E, Grandjean P, Crofton KM, Aschner M, Goldberg A, Heinonen T, Hessel EVS, Hogberg HT, Bennekou SH, Lein PJ, Leist M, Mundy WR, Paparella M, Piersma AH, Sachana M, Schmuck G, Solecki R, Terron A, Monnet-Tschudi F, Wilks MF, Witters H, Zurich MG, Bal-Price A
Toxicology and Applied Pharmacology, 1 Sep 2018
Effect of the catechol-O-methyltransferase inhibitors tolcapone and entacapone on fatty acid metabolism in HepaRG cells
Grünig D, Felser A, Duthaler U, Bouitbir J, Krähenbühl S
Toxicological Sciences, 1 Aug 2018
High-dose immunosuppression to prevent death after paraquat self-poisoning - a randomised controlled trial
Gawarammana I, Buckley NA, Mohamed F, Naser K, Jeganathan K, Ariyananada PL, Wunnapuk K, Dobbins TA, Tomenson JA, Wilks MF, Eddleston M, Dawson AH
Clinical Toxicology (Phila), 31 Jul 2018
Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug
Berger B, Bachmann F, Duthaler U, Krähenbühl S, Haschke M
Frontiers in Pharmacology, 24 Jul 2018
Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity
Bal-Price A, Hogberg HT, Crofton KM, Daneshian M, FitzGerald RE, Fritsche E, Heinonen T, Hougaard Bennekou S, Klima S, Piersma AH, Sachana M, Shafer TJ, Terron A, Monnet-Tschudi F, Viviani B, Waldmann T, Westerink RHS, Wilks MF, Witters H, Zurich MG, Leist M
ALTEX, 9 Jul 2018
Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways
Villeneuve DL, Landesmann B, Allavena P, Ashley N, Bal-Price A, Corsini E, Halappanavar S, Hussell T, Laskin D, Lawrence T, Nikolic-Paterson D, Pallardy M, Paini A, Pieters R, Roth R, Tschudi-Monnet F
Toxicological Sciences, 1 Jun 2018
Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells
Grünig D, Duthaler U, Krähenbühl S
Frontiers in Pharmacology, 23 Apr 2018
Mechanisms of toxicity associated with six tyrosine kinase inhibitors in human hepatocyte cell lines
Mingard C, Paech F, Bouitbir J, Krähenbühl S
Journal of Applied Toxicology, 31 Mär 2018
Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis
Engeli RT, Fürstenberger C, Kratschmar DV, Odermatt A
Heliyon, 28 Feb 2018